SCHEMBL9687007

SCHEMBL9687007

COc1cc(C=O)cc(C(=O)O)c1O.[CaH2]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.50
PTGS2 P35354 2/20 0.50
PTGS1 P23219 1/20 0.50
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
PTPN6 P29350 1/20 0.49
TDP1 Q9NUW8 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TRIM24 O15164 1/20 0.49
HPGD P15428 1/20 0.49
ALDH5A1 P51649 1/20 0.49
ABAT P80404 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA3 P07451 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954196 0.98 PKM (0.51) PKMPTGS2PTGS1PTPN2PTPN1
SCHEMBL1981806 0.98 PKM (0.51) PKMPTGS2PTGS1PTPN2PTPN1
SCHEMBL9686354 0.97 PKM (0.50) PKMPTGS2PTGS1PTPN2PTPN1
Syringaldehyde SCHEMBL31412823 0.84 PKM (0.62) PKMPTGS2PTGS1TDP1ALDH1A1
SCHEMBL4756891 0.83 ALDH1A1 (0.49) PKMPTGS2PTGS1TDP1ALDH1A1
SCHEMBL31454779 0.83 PKM (0.50) PKMPTGS2PTGS1PTPN2PTPN1
SCHEMBL4757716 0.83 KMT2A (0.49) PKMPTGS2PTGS1TDP1ALDH1A1
SCHEMBL9687000 0.82 CYP1A2 (0.50) PKMPTGS2PTGS1TDP1ALDH1A1
SCHEMBL198173 0.82 PKM (0.57) PKMPTGS2PTGS1PTPN2PTPN1
Potassium Ion SCHEMBL9688312 0.82 ALDH1A1 (0.47) PKMPTGS2PTGS1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514202-A2 Smoking compositions containing a vanillin-release additive Philip Morris Products Inc. (US) 1992-11-19 EP claimed
US-5144965-A Vanillin carboxylate type additive pyrolyzes to ethyl vanillin; cigarettes PHILIP MORRIS INCORPORATED (US) 1992-09-08 US claimed
EP-0514202-A2 Smoking compositions containing a vanillin-release additive Philip Morris Products Inc. (US) 1992-11-19 EP disclosed
US-5144965-A Vanillin carboxylate type additive pyrolyzes to ethyl vanillin; cigarettes PHILIP MORRIS INCORPORATED (US) 1992-09-08 US disclosed