Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755935 | 0.87 | MAPT (0.56) | LMNAACHEABCG2MAPTSMN1; SMN2 | |
| SCHEMBL4755807 | 0.86 | GBA1 (0.63) | LMNAACHEABCG2MAPTSMN1; SMN2 | |
| SCHEMBL4755874 | 0.84 | HIF1A (0.67) | LMNAACHEMAPTSMN1; SMN2GBA1 | |
| SCHEMBL4096827 | 0.83 | ACP1 (0.70) | LMNAABCG2MAPTACP1ALDH1A1 | |
| SCHEMBL4755906 | 0.82 | HIF1A (0.56) | LMNAACHEABCG2MAPTSMN1; SMN2 | |
| SCHEMBL4090937 | 0.82 | CYP3A4 (0.67) | LMNAABCG2MAPTSMN1; SMN2ROCK2 | |
| SCHEMBL4084433 | 0.82 | ACP1 (0.71) | LMNAABCG2MAPTACP1ALDH1A1 | |
| SCHEMBL4755806 | 0.81 | RAB9A (0.69) | LMNAACHEABCG2MAPTSMN1; SMN2 | |
| SCHEMBL4090305 | 0.80 | HTT (0.66) | LMNAABCG2MAPTSMN1; SMN2ACP1 | |
| SCHEMBL4095774 | 0.80 | GBA1 (0.61) | ABCG2MAPTACP1ROCK2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |