Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755891 | 0.87 | LMNA (0.53) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4755906 | 0.84 | HIF1A (0.56) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4755807 | 0.81 | GBA1 (0.63) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4755874 | 0.81 | HIF1A (0.67) | MAPTLMNAACHEGBA1CYP1A2 | |
| SCHEMBL4097902 | 0.80 | GBA1 (0.61) | MAPTABCG2GBA1ACP1CYP1A2 | |
| SCHEMBL4755806 | 0.79 | RAB9A (0.69) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4085133 | 0.78 | MEN1 (0.64) | MAPTLMNAABCG2GBA1CYP1A2 | |
| SCHEMBL4754102 | 0.77 | KMT2A (0.72) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4753586 | 0.76 | KMT2A (0.56) | MAPTLMNAACHEABCG2GBA1 | |
| SCHEMBL4756735 | 0.76 | KMT2A (0.58) | MAPTLMNAACHEABCG2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |