Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.63 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475383 | 0.86 | HTR6 (0.80) | HTR6HPGDSMN1; SMN2ACLYHTR3E | |
| Hydrochloric Acid SCHEMBL1748287 | 0.85 | HTR6 (0.79) | HTR6HPGDSMN1; SMN2HTR3EHTR3B | |
| SCHEMBL475388 | 0.83 | HPGD (0.46) | HTR6HPGDSMN1; SMN2ACLYCNR1 | |
| Hydrochloric Acid SCHEMBL1748277 | 0.82 | HPGD (0.46) | HTR6HPGDSMN1; SMN2ACLYCNR1 | |
| SCHEMBL1747990 | 0.80 | HTR6 (0.68) | HTR6HPGDSMN1; SMN2CNR1HTR3E | |
| Hydrochloric Acid SCHEMBL1748809 | 0.79 | HTR6 (0.67) | HTR6HPGDSMN1; SMN2CNR1HTR3E | |
| SCHEMBL5021125 | 0.78 | HTR6 (0.78) | HTR6HPGDSMN1; SMN2ACLYSOS1 | |
| SCHEMBL475397 | 0.78 | HTR6 (1.00) | HTR6HPGDSMN1; SMN2ACLYSOS1 | |
| SCHEMBL1748904 | 0.78 | HTR6 (1.00) | HTR6HPGDSMN1; SMN2ACLYSOS1 | |
| SCHEMBL1748316 | 0.78 | HTR6 (1.00) | HTR6HPGDSMN1; SMN2ACLYSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2037925-B1 | COMBINATIONS COMPRISING 5HT6 MODULATORS AND CHOLINESTERASE INHIBITORS | GALENEA CORP (US) | 2012-02-01 | — | — | EP | disclosed |