Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12618333 | 0.91 | PDE4B (0.45) | GPR119PDE4BMAPTTACR1PDE4A | |
| SCHEMBL12652817 | 0.91 | PDE4B (0.45) | GPR119PDE4BMAPTTACR1PDE4A | |
| SCHEMBL1105757 | 0.90 | GPR119 (0.49) | GPR119PDE4BTACR1PDE4APDE4C | |
| SCHEMBL1105975 | 0.90 | GPR119 (0.49) | GPR119PDE4BTACR1PDE4APDE4C | |
| SCHEMBL3004868 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 | |
| SCHEMBL4004318 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 | |
| SCHEMBL3010603 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 | |
| SCHEMBL7904145 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 | |
| SCHEMBL1105755 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 | |
| SCHEMBL1105921 | 0.89 | PKM (0.51) | GPR119MAPTTACR1USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |
| US-20080275085-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275085-A1 | Piperidine derivative and use thereof | TACR2, TACR1, PRLHR | GPR119 105/4885PDE4B 1291/4885MAPT 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.