Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594362 | 0.89 | TSHR (0.56) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL5677947 | 0.87 | LMNA (0.62) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL903883 | 0.87 | TSHR (0.58) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL6201009 | 0.87 | MAOB (0.59) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL27363692 | 0.85 | TSHR (0.56) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL21098621 | 0.85 | RAB9A (0.63) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL3120643 | 0.84 | TSHR (0.50) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL9478520 | 0.83 | KCNA3 (0.56) | MAOBAPPTSHRLTA4H | |
| 4-Benzyloxyaniline SCHEMBL171449 | 0.83 | MAOB (1.00) | MAOBRAB9AGAAMAPTMAOA | |
| SCHEMBL5583741 | 0.82 | RAB9A (0.70) | MAOBRAB9AGAAMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| US-4168264-A | PRINTING AND DYEING OF POLYACRYLONITRILE TEXTILES | CIBA-GEIGY CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |