Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633724 | 0.90 | SLC6A1 (0.50) | TSHRSLC6A1SLC6A11SLC6A13LMNA | |
| SCHEMBL5730343 | 0.89 | GABRP (0.43) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| SCHEMBL4754523 | 0.85 | CHRNB2 (0.34) | HRH3HPGDBTK | |
| SCHEMBL1034237 | 0.83 | HRH3 (0.41) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| SCHEMBL1415306 | 0.83 | HRH3 (0.41) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| SCHEMBL951872 | 0.83 | HRH3 (0.41) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| Hydrochloric Acid SCHEMBL15904240 | 0.81 | HRH3 (0.40) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| Hydrochloric Acid SCHEMBL31172943 | 0.81 | HRH3 (0.40) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| Ammonia Solution, Strong SCHEMBL19327469 | 0.81 | HRH3 (0.40) | GABRA5GABRB2TSHRGABRA1GABRA4 | |
| Hydrochloric Acid SCHEMBL29581714 | 0.81 | HRH3 (0.40) | GABRA5GABRB2TSHRGABRA1GABRA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | claimed |