Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL30988876 | 0.84 | KMT2A (0.44) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| Benzimidazole SCHEMBL28194023 | 0.84 | RAB9A (0.47) | KMT2AKDM4EALDH1A1RAB9AHPGD | |
| Benzimidazole SCHEMBL28131872 | 0.82 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1RAB9AHPGD | |
| Benzimidazole SCHEMBL28132665 | 0.82 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1RAB9AHPGD | |
| Benzimidazole SCHEMBL1353216 | 0.82 | CTNNB1 (0.46) | EGFRMAPK10DDR1KDM4EALDH1A1 | |
| Salicylic Acid SCHEMBL11884489 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| Salicylic Acid SCHEMBL11884485 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| Benzimidazole SCHEMBL2496637 | 0.80 | RAB9A (0.49) | KMT2AKDM4EALDH1A1RAB9AHPGD | |
| Phenanthrene SCHEMBL28066912 | 0.80 | SMN1; SMN2 (0.48) | MAPK10KDM4EALDH1A1RAB9AHPGD | |
| Anthranilic Acid SCHEMBL9635430 | 0.79 | KDM4E (0.46) | MAPK10KMT2AKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551902-B1 | ANISOTROPIC FILMS BASED ON 1,8-NAPHTHOYLENE-1 ,2 -BENZIMIDAZOLE SULFONATES AND LYOTROPIC LIQUID CRYSTAL SYSTEMS AND METHODS FOR MAKING | NITTO DENKO CORP (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7262305-B2 | Anisotropic films based on 1,8-naphthoylene-1′,2′-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making | NITTO DENKO CORPORATION (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1551902-A4 | ANISOTROPIC FILMS BASED ON 1,8-NAPHTHOYLENE-1 ,2 -BENZIMIDAZOLE SULFONATES AND LYOTROPIC LIQUID CRYSTAL SYSTEMS AND METHODS FOR MAKING | NITTO DENKO CORP (JP) | 2006-05-17 | — | — | EP | disclosed |
| US-7026019-B2 | Anisotropic films based on 1,8-naphthoylene-1′,2′-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making | NITTO DENKO CORPORATION (JP) | 2006-04-11 | — | — | US | disclosed |
| US-20060062932-A1 | Anisotropic films based on 1,8-naphthoylene-1'2'-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making | DUTOVA TATYANA Y | 2006-03-23 | — | — | US | disclosed |
| EP-1551902-A2 | ANISOTROPIC FILMS BASED ON 1,8-NAPHTHOYLENE-1 ,2 -BENZIMIDAZOLE SULFONATES AND LYOTROPIC LIQUID CRYSTAL SYSTEMS AND METHODS FOR MAKING | Optiva, Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20040058091-A1 | Anisotropic films based on 1,8-naphthoylene-1',2'-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making | INSOLVENCY SERVICES GROUP, INC. | 2004-03-25 | — | — | US | disclosed |
| WO-2004003599-A2 | ANISOTROPIC FILMS BASED ON 1,8-NAPHTHOYLENE-1',2'-BENZIMIDAZOLE SULFONATES AND LYOTROPIC LIQUID CRYSTAL SYSTEMS AND METHODS FOR MAKING | OPTIVA, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060062932-A1 | Anisotropic films based on 1,8-naphthoylene-1'2'-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making | LSS, LASP1, LYAR | NR4A1 1564/4885NR4A2 3164/4885NR4A3 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.