Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 5/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101749 | 0.84 | TGFBR1 (0.37) | ADRB2ADRB1ADRB3MMETGFBR1 | |
| SCHEMBL3101742 | 0.79 | TGFBR1 (0.39) | MMETGFBR1 | |
| SCHEMBL4756588 | 0.78 | TGFBR1 (0.45) | MMETGFBR1 | |
| SCHEMBL3106337 | 0.77 | TGFBR1 (0.37) | MMETGFBR1 | |
| SCHEMBL3098561 | 0.77 | TGFBR1 (0.37) | MMETGFBR1 | |
| SCHEMBL2234720 | 0.74 | MME (0.53) | MMETGFBR1ALDH1A1PLGPLAU | |
| SCHEMBL2234718 | 0.74 | MME (0.53) | MMETGFBR1ALDH1A1PLGPLAU | |
| SCHEMBL12233224 | 0.73 | ADRB2 (0.49) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11027091 | 0.71 | ADRB2 (0.48) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11024696 | 0.71 | ADRB2 (0.48) | ADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | disclosed |