Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985512 | 1.00 | CRHR1 (0.35) | CRHR1KMT2ACCNA2CDK2CDK5 | |
| SCHEMBL13985420 | 0.91 | CCNA2 (0.35) | CRHR1KMT2ACCNA2CDK2CDK5 | |
| SCHEMBL4756584 | 0.91 | CCNA2 (0.35) | CRHR1KMT2ACCNA2CDK2CDK5 | |
| SCHEMBL4755090 | 0.87 | CRHR1 (0.37) | CRHR1KMT2ACCNA2CDK2CDK5 | |
| SCHEMBL13985510 | 0.87 | CRHR1 (0.37) | CRHR1KMT2ACCNA2CDK2CDK5 | |
| SCHEMBL4753289 | 0.76 | MAT2A (0.34) | CRHR1MAT2A | |
| SCHEMBL4753340 | 0.68 | DRD1 (0.39) | CRHR1KMT2AMAT2ASMN1; SMN2GAA | |
| SCHEMBL13985230 | 0.68 | DRD1 (0.39) | CRHR1KMT2AMAT2ASMN1; SMN2GAA | |
| SCHEMBL13985422 | 0.67 | MAT2A (0.36) | CRHR1MAT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL4755608 | 0.67 | MAT2A (0.36) | CRHR1MAT2ASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |