Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 16/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985503 | 0.82 | USP14 (0.35) | USP14POLBUSP5USP7 | |
| SCHEMBL4755691 | 0.81 | USP14 (0.36) | USP14USP5USP7 | |
| SCHEMBL13985512 | 0.76 | CRHR1 (0.35) | MAT2ACRHR1 | |
| SCHEMBL4756656 | 0.76 | CRHR1 (0.35) | MAT2ACRHR1 | |
| SCHEMBL13985228 | 0.73 | CRHR1 (0.35) | CRHR1USP14USP5USP7 | |
| SCHEMBL13985230 | 0.71 | DRD1 (0.39) | MAT2ACRHR1POLB | |
| SCHEMBL4753340 | 0.71 | DRD1 (0.39) | MAT2ACRHR1POLB | |
| SCHEMBL4755555 | 0.69 | PDE4B (0.35) | USP14 | |
| SCHEMBL4755548 | 0.69 | PDE4B (0.35) | USP14 | |
| SCHEMBL4755225 | 0.68 | DRD1 (0.40) | MAT2ACRHR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |