Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757731 | 0.86 | KCNA3 (0.45) | CHRM3CHRM2CHRM1KCNA3RAB9A | |
| SCHEMBL4789918 | 0.80 | CHRM3 (0.36) | CHRM3CHRM2CHRM1CCR1 | |
| SCHEMBL4757575 | 0.76 | CHRM3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4789739 | 0.76 | CHRM3 (0.36) | CHRM3CHRM2CHRM1CCR1 | |
| SCHEMBL4789432 | 0.73 | ADRA1D (0.42) | — | |
| SCHEMBL4788465 | 0.73 | CHRM3 (0.32) | CHRM3 | |
| SCHEMBL4617789 | 0.70 | CHRM2 (0.48) | CHRM3CHRM2CHRM1CCR1 | |
| SCHEMBL4619558 | 0.69 | CHRM2 (0.43) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4758052 | 0.68 | DRD2 (0.42) | CHRM3CHRM2CHRM1CCR1KCNA3 | |
| SCHEMBL13271382 | 0.66 | CYP2D6 (0.44) | CHRM3CHRM2CHRM1CCR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |