Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757519 | 0.84 | KCNA3 (0.54) | DRD2DRD3KCNA3CCR3CHRM2 | |
| SCHEMBL4756790 | 0.79 | CHRM3 (0.39) | DRD2DRD3KCNA3CHRM2CHRM1 | |
| SCHEMBL4757548 | 0.78 | CHRM3 (0.46) | CHRM2CHRM1CHRM3CCR1 | |
| SCHEMBL4789529 | 0.77 | ADRA1A (0.41) | DRD2DRD3CHRM2CHRM1CHRM3 | |
| SCHEMBL4757759 | 0.77 | CCR1 (0.43) | DRD2DRD3KCNA3CCR3CHRM2 | |
| SCHEMBL4755473 | 0.74 | GRIN2B (0.40) | FUCA1 | |
| SCHEMBL4757528 | 0.74 | DRD2 (0.42) | DRD2DRD3FUCA1ACHE | |
| SCHEMBL11413096 | 0.71 | FUCA1 (0.60) | DRD2DRD3CCR3FUCA1ACHE | |
| SCHEMBL4757520 | 0.71 | CHRM3 (0.48) | CHRM2CHRM3FUCA1 | |
| SCHEMBL25333858 | 0.70 | DRD2 (0.50) | DRD2DRD3FUCA1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |