SCHEMBL4756802

SCHEMBL4756802

NC(=O)C(CC1C2CN(Cc3ccccc3)CC21)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 5/20 0.47
S1PR5 Q9H228 4/20 0.45
S1PR1 P21453 2/20 0.45
FUCA1 P04066 2/20 0.43
GRK5 P34947 1/20 0.41
CDK8 P49336 1/20 0.41
CHRM2 P08172 2/20 0.41
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4757732 0.89 S1PR5 (0.47) CHRM3S1PR5S1PR1FUCA1GRK5
SCHEMBL4757520 0.87 CHRM3 (0.48) CHRM3S1PR5S1PR1FUCA1CHRM2
SCHEMBL4617489 0.83 CHRM3 (0.41) CHRM3S1PR5S1PR1FUCA1GRK5
SCHEMBL4757574 0.83 CHRM3 (0.44) CHRM3S1PR5S1PR1CHRM2
SCHEMBL4757575 0.79 CHRM3 (0.48) CHRM3CHRM2
SCHEMBL8878260 0.79 CHRM3 (0.56) CHRM3
Water SCHEMBL10720338 0.77 BCHE (0.51) CHRM3
SCHEMBL4758054 0.76 CHRM3 (0.49) CHRM3CHRM2
SCHEMBL4788078 0.74 CHRM3 (0.43) CHRM3CHRM2GRIN2B
SCHEMBL20875290 0.74 S1PR5 (0.54) S1PR5S1PR1FUCA1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008117229-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2008-10-02 WO claimed
WO-2008117229-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2008-10-02 WO disclosed