Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617489 | 0.86 | CHRM3 (0.41) | CHRM3S1PR1S1PR5CHRM2CHRM1 | |
| SCHEMBL4757732 | 0.85 | S1PR5 (0.47) | CHRM3S1PR1S1PR5LMNAALDH1A1 | |
| SCHEMBL4756802 | 0.83 | CHRM3 (0.47) | CHRM3S1PR1S1PR5CHRM2 | |
| SCHEMBL25358242 | 0.79 | SIGMAR1 (0.54) | ATML3MBTL1S1PR1S1PR5MAPK1 | |
| SCHEMBL25358239 | 0.79 | SIGMAR1 (0.54) | ATML3MBTL1S1PR1S1PR5MAPK1 | |
| SCHEMBL19971674 | 0.76 | ALDH1A1 (0.55) | ATML3MBTL1S1PR1S1PR5MAPK1 | |
| SCHEMBL18517409 | 0.76 | ALDH1A1 (0.55) | ATML3MBTL1S1PR1S1PR5MAPK1 | |
| SCHEMBL8922062 | 0.76 | ALDH1A1 (0.55) | ATML3MBTL1S1PR1S1PR5MAPK1 | |
| SCHEMBL4617491 | 0.75 | CHRM3 (0.48) | CHRM3S1PR1S1PR5BCHEACHE | |
| SCHEMBL13102892 | 0.74 | HTR4 (0.49) | ATML3MBTL1S1PR1S1PR5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |