Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879133 | 0.87 | CHRM3 (0.57) | CHRM3ACHECCR3 | |
| Water SCHEMBL10720338 | 0.84 | BCHE (0.51) | CHRM3ACHEBCHE | |
| SCHEMBL4430306 | 0.83 | CHRM3 (0.55) | CHRM3CCR3 | |
| SCHEMBL4757520 | 0.80 | CHRM3 (0.48) | CHRM3 | |
| SCHEMBL10519952 | 0.79 | CCR3 (0.59) | CHRM3ACHEBCHECCR3CXCR4 | |
| SCHEMBL4756802 | 0.79 | CHRM3 (0.47) | CHRM3 | |
| SCHEMBL9248078 | 0.78 | KMT2A (0.57) | CCR3 | |
| SCHEMBL26096555 | 0.78 | ACHE (0.72) | GAAACHEBCHECCR3 | |
| SCHEMBL1138416 | 0.77 | ACHE (0.76) | CHRM3ACHEBCHECCR3 | |
| SCHEMBL4854037 | 0.77 | GAA (0.64) | GAAACHEBCHECCR3CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607950-A | IRRITABLE BOWEL SYNDROME | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0508988-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1991010647-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |