SCHEMBL4756944

SCHEMBL4756944

CCNc1c(F)c(F)c2cn(-c3c(C(C)C)cccc3C(C)C)cc2c1F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.38
DPP4 P27487 2/20 0.38
SOAT1 P35610 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4756913 0.75 CA12 (0.40) ANPEPDPP4
SCHEMBL2476501 0.74 ANPEP (0.59) ANPEPDPP4SMN1; SMN2
SCHEMBL4756155 0.72 CA12 (0.36) ANPEPDPP4
SCHEMBL2477491 0.70 ANPEP (0.61) ANPEPDPP4SMN1; SMN2
SCHEMBL11107355 0.70 SMN1; SMN2 (0.47) SOAT1SMN1; SMN2
SCHEMBL20260822 0.66 GABRA1 (0.38) ANPEPDPP4SOAT1SMN1; SMN2
SCHEMBL12852058 0.65 MAPK1 (0.51) SOAT1SMN1; SMN2
SCHEMBL2479575 0.62 ANPEP (0.35) ANPEPDPP4SMN1; SMN2
SCHEMBL8910857 0.62 TSHR (0.33)
SCHEMBL28045533 0.61 GABRA1 (0.46) ANPEPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008155593-A2 PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES AVICOR KUTATO (HU) 2008-12-24 WO claimed
WO-2008155593-A2 PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES AVICOR KUTATO (HU) 2008-12-24 WO disclosed