Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480081 | 0.94 | ANPEP (0.37) | ANPEPDPP4C5AR1SMN1; SMN2 | |
| SCHEMBL2481752 | 0.76 | ANPEP (0.36) | ANPEPDPP4KDM4EMEN1KMT2A | |
| SCHEMBL2480594 | 0.76 | ANPEP (0.55) | ANPEPDPP4SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2477514 | 0.73 | ANPEP (0.58) | ANPEPDPP4SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12655982 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2478533 | 0.72 | ANPEP (0.38) | ANPEPDPP4KDM4EMEN1KMT2A | |
| SCHEMBL6926706 | 0.63 | ALDH1A1 (0.42) | ANPEPDPP4SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL4756944 | 0.62 | ANPEP (0.38) | ANPEPDPP4SMN1; SMN2 | |
| SCHEMBL2520538 | 0.62 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12828379 | 0.62 | L3MBTL1 (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373618-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | Avidin KFT (HU) | 2011-10-12 | — | — | EP | claimed |
| EP-2373618-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | Avidin KFT (HU) | 2011-10-12 | — | — | EP | disclosed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | disclosed |