Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513922 | 0.83 | LMNA (0.42) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL3237667 | 0.83 | FOLH1 (0.43) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL2921467 | 0.82 | SLC1A3 (0.47) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL10597893 | 0.78 | CA2 (0.45) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4753845 | 0.78 | CA2 (0.45) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27784485 | 0.78 | MMP1 (0.48) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL4755497 | 0.77 | MGAM (0.46) | LMNACA2MAPK1SLC1A3SLC1A2 | |
| SCHEMBL1823767 | 0.77 | MGAM (0.46) | LMNACA2MAPK1SLC1A3SLC1A2 | |
| SCHEMBL12224068 | 0.76 | LMNA (0.47) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL4753693 | 0.76 | MMP1 (0.47) | LMNAMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |