Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | DRD4 | P21917 | 6/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | KLK1 | P06870 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757112 | 0.88 | DRD2 (0.38) | DRD2DRD4DRD3GNRHRPOLB | |
| SCHEMBL210615 | 0.87 | KDM4E (0.44) | MAPTALDH1A1L3MBTL1NPBWR1MCHR1 | |
| SCHEMBL208800 | 0.86 | AURKA (0.43) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL209448 | 0.83 | POLB (0.52) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL208834 | 0.83 | OPRM1 (0.48) | MAPTALDH1A1L3MBTL1NPBWR1MCHR1 | |
| SCHEMBL209785 | 0.83 | AURKA (0.47) | DRD2DRD4DRD3POLBMAPT | |
| SCHEMBL2731281 | 0.82 | ALDH1A1 (0.52) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL207969 | 0.81 | AURKA (0.46) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL4757119 | 0.79 | POLB (0.38) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL208825 | 0.78 | MAPT (0.45) | POLBMAPTALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |