Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811746 | 0.80 | CYP2D6 (0.36) | DRD2DRD3FUCA1HRH3GRIN2B | |
| SCHEMBL4191012 | 0.79 | FUCA1 (0.50) | DRD2DRD3FUCA1HRH3ACHE | |
| SCHEMBL4757519 | 0.78 | KCNA3 (0.54) | DRD2DRD3 | |
| SCHEMBL4757520 | 0.78 | CHRM3 (0.48) | FUCA1GRIN2B | |
| SCHEMBL11413096 | 0.75 | FUCA1 (0.60) | DRD2DRD3FUCA1ACHEBCHE | |
| SCHEMBL4755473 | 0.74 | GRIN2B (0.40) | FUCA1GRIN2B | |
| SCHEMBL16837173 | 0.74 | FUCA1 (0.58) | DRD2DRD3FUCA1ACHEBCHE | |
| SCHEMBL4758052 | 0.74 | DRD2 (0.42) | DRD2DRD3FUCA1ACHE | |
| SCHEMBL4198217 | 0.73 | FUCA1 (0.54) | DRD2DRD3FUCA1ACHEBCHE | |
| SCHEMBL21777260 | 0.73 | FUCA1 (0.53) | DRD2DRD3FUCA1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |