Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | XIAP | P98170 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 4/20 | 0.63 |
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | LTA4H | P09960 | 7/20 | 0.63 |
| ▸ | LAP3 | P28838 | 1/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065556 | 1.00 | SLC7A5 (0.67) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL659105 | 0.98 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL288912 | 0.98 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL515522 | 0.98 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL16816702 | 0.97 | SLC7A5 (0.67) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL16816706 | 0.97 | SLC7A5 (0.67) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL12379285 | 0.94 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Trifluoroacetic Acid SCHEMBL8208389 | 0.92 | PTPN1 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL21340321 | 0.90 | ITGB3 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL28633098 | 0.89 | LTA4H (0.70) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| EP-1636164-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LTD. (IN) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005019152-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |