Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700558 | 0.80 | CRHR1 (0.37) | CRHR1HRH4 | |
| SCHEMBL3364667 | 0.72 | CRHR1 (0.40) | CRHR1HRH4 | |
| SCHEMBL4702277 | 0.71 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL4702273 | 0.70 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL4702940 | 0.69 | CRHR1 (0.43) | CRHR1HRH4 | |
| SCHEMBL3364082 | 0.69 | CRHR1 (0.45) | CRHR1HRH4 | |
| SCHEMBL4702339 | 0.69 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL4698860 | 0.69 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL4698858 | 0.68 | CRHR1 (0.45) | CRHR1 | |
| Hydrochloric Acid SCHEMBL4698143 | 0.68 | CRHR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |