Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757855 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1ERN1MAPK1 | |
| SCHEMBL4756882 | 0.76 | PTGS2 (0.46) | PTPN1PTPN2PTPN6ALDH1A1MAPK1 | |
| SCHEMBL4756919 | 0.74 | PTPN1 (0.69) | PTPN1PTPN2PTPN6ERN1AKR1C4 | |
| SCHEMBL31497642 | 0.74 | PTPN1 (0.69) | PTPN1PTPN2PTPN6ERN1AKR1C4 | |
| SCHEMBL4757889 | 0.73 | CA12 (0.46) | PTPN1PTPN2PTPN6LMNAALDH1A1 | |
| SCHEMBL4756917 | 0.73 | ERN1 (0.50) | PTPN1PTPN2PTPN6ALDH1A1ERN1 | |
| SCHEMBL373244 | 0.71 | ERN1 (0.52) | PTPN1PTPN2PTPN6ALDH1A1ERN1 | |
| SCHEMBL23308705 | 0.69 | TP53 (0.43) | ALDH1A1CA2 | |
| SCHEMBL2511971 | 0.69 | PTPN1 (0.45) | PTPN1PTPN2PTPN6LMNAGFER | |
| SCHEMBL4788121 | 0.69 | PTP4A1 (0.47) | PTPN1PTPN2PTPN6ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879661-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |