Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755525 | 0.91 | KCNA3 (0.48) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL4756754 | 0.87 | KCNA3 (0.49) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL4757577 | 0.77 | KCNA3 (0.60) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL6258542 | 0.75 | DRD2 (0.68) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL4756747 | 0.75 | CHRM3 (0.47) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL8070530 | 0.72 | OPRM1 (0.44) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL8879197 | 0.71 | KCNA3 (0.49) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL4757758 | 0.70 | CCR3 (0.62) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL11600502 | 0.70 | KCNA3 (0.61) | KCNA3RAB9ANPSR1DRD2DRD4 | |
| SCHEMBL5857455 | 0.69 | ATM (0.57) | KCNA3RAB9ANPSR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |