Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073918 | 0.80 | CCR1 (0.42) | OPRM1CYP2D6KCNA3CHRM2CHRM1 | |
| SCHEMBL8070848 | 0.74 | CHRM3 (0.43) | CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL4757748 | 0.72 | KCNA3 (0.50) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL6258542 | 0.69 | DRD2 (0.68) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL4755525 | 0.67 | KCNA3 (0.48) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL4014770 | 0.66 | DRD2 (0.65) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL2521449 | 0.66 | DRD2 (0.59) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL4756754 | 0.65 | KCNA3 (0.49) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL8879197 | 0.65 | KCNA3 (0.49) | OPRM1DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL5857455 | 0.64 | ATM (0.57) | OPRM1DRD2DRD4DRD3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020449-A1 | IMIDAZOLINE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-07-19 | — | — | EP | claimed |
| EP-1020449-A1 | IMIDAZOLINE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |