Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium SCHEMBL4757927 | 0.98 | CALCRL (0.40) | CALCRLSMN1; SMN2MAPTL3MBTL1MEN1 | |
| Lithium Ion SCHEMBL4757919 | 0.87 | CALCRL (0.39) | CALCRLSMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL4758257 | 0.82 | RXRA (0.43) | CALCRLSMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL4757749 | 0.81 | CALCRL (0.38) | CALCRLSMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL4758251 | 0.76 | CALCRL (0.46) | CALCRLSMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL4757886 | 0.75 | NOTUM (0.48) | CALCRLSMN1; SMN2MAPTL3MBTL1NOTUM | |
| SCHEMBL4755690 | 0.74 | CALCRL (0.40) | CALCRLSMN1; SMN2MAPTNOTUMPIK3CD | |
| SCHEMBL4757784 | 0.73 | CALCRL (0.53) | CALCRLSMN1; SMN2MAPTL3MBTL1NOTUM | |
| Lithium SCHEMBL4757890 | 0.72 | NOTUM (0.48) | CALCRLSMN1; SMN2MAPTL3MBTL1NOTUM | |
| SCHEMBL4756909 | 0.72 | RXRA (0.37) | CALCRLSMN1; SMN2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |