Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850863 | 0.75 | MAPT (0.53) | ALDH1A1KDM4EMAPTGAAMAPK1 | |
| SCHEMBL11446696 | 0.74 | FDPS (0.51) | ALDH1A1KDM4ETDP1POLBCTDSP1 | |
| SCHEMBL11446697 | 0.74 | FDPS (0.51) | ALDH1A1KDM4ETDP1POLBCTDSP1 | |
| SCHEMBL29338761 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL8378021 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL8378025 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL8379977 | 0.70 | HTT (0.48) | ALDH1A1TDP1MAPTGAAMAPK1 | |
| SCHEMBL8379979 | 0.70 | HTT (0.48) | ALDH1A1TDP1MAPTGAAMAPK1 | |
| SCHEMBL16535350 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL16535351 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001126-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBATERIAL AGENTS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |