⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306807 | 0.71 | NOS2 (0.39) | — | |
| SCHEMBL6233876 | 0.64 | — | — | |
| SCHEMBL8854822 | 0.63 | BACE1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL7013830 | 0.63 | — | — | |
| SCHEMBL1979240 | 0.61 | — | — | |
| SCHEMBL424369 | 0.61 | — | — | |
| SCHEMBL20967802 | 0.61 | — | — | |
| SCHEMBL21215341 | 0.57 | — | — | |
| SCHEMBL9712194 | 0.56 | — | — | |
| SCHEMBL2117309 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957480-A1 | SUBSTITUTED OXINDOL-DERIVATIVES, MEDICAMENTS CONTAINING SAID DERIVATIVES AND USE THEREOF | Abbott GmbH & Co. KG (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1861392-A2 | SUBSTITUTED OXINDOL DERIVATIVES, DRUGS CONTAINING SAID DERIVATIVES AND THE USE THEREOF | Abbott GmbH & Co. KG (DE) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007063123-A1 | SUBSTITUTED OXINDOL-DERIVATIVES, MEDICAMENTS CONTAINING SAID DERIVATIVES AND USE THEREOF | ABBOTT GMBH & CO. KG (DE) | 2007-06-07 | — | — | WO | disclosed |
| WO-2006100082-A2 | SUBSTITUTED OXINDOL DERIVATIVES, DRUGS CONTAINING SAID DERIVATIVES AND THE USE THEREOF | ABBOTT GMBH & CO. KG (DE) | 2006-09-28 | — | — | WO | disclosed |