Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624375 | 0.79 | NOS2 (0.35) | NOS2KDM4EALDH1A1HPGD | |
| SCHEMBL13632710 | 0.74 | GAA (0.34) | NOS2 | |
| SCHEMBL15813511 | 0.71 | NOS2 (0.31) | NOS2 | |
| SCHEMBL4758533 | 0.71 | — | — | |
| SCHEMBL13038795 | 0.68 | TSHR (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL5904469 | 0.67 | TNKS2 (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL19999997 | 0.66 | RAB9A (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5891203 | 0.64 | TTK (0.36) | NOS2 | |
| SCHEMBL5937401 | 0.64 | — | — | |
| SCHEMBL2643485 | 0.63 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |