Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPRF | P10586 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163147 | 0.74 | IDO1 (0.31) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL13038795 | 0.67 | TSHR (0.36) | MAOAMAOB | |
| SCHEMBL5904469 | 0.66 | TNKS2 (0.36) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL5531635 | 0.65 | TNKS2 (0.36) | IDO1PTPRCPTPN1 | |
| SCHEMBL3616173 | 0.64 | MEN1 (0.34) | — | |
| SCHEMBL4758533 | 0.63 | — | — | |
| SCHEMBL17306807 | 0.62 | NOS2 (0.39) | — | |
| SCHEMBL15624375 | 0.62 | NOS2 (0.35) | — | |
| SCHEMBL4994523 | 0.62 | — | — | |
| SCHEMBL13632710 | 0.61 | GAA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069308-B1 | AZONAFIDE DERIVED TUMOR AND CANCER TARGETING COMPOUNDS | GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SER (US) | 2017-03-29 | — | — | EP | disclosed |
| US-5703089-A | ANTICANCER AGENTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |