Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198529 | 0.89 | IDO1 (0.58) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL2081746 | 0.85 | MAPT (0.71) | MAPTALDH1A1CYP19A1HTTLMNA | |
| SCHEMBL5286113 | 0.85 | DRD2 (0.73) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL8456712 | 0.84 | ALDH1A1 (0.62) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL27712803 | 0.84 | TSHR (0.60) | MAPTALDH1A1CYP19A1HTTLMNA | |
| SCHEMBL13264901 | 0.84 | ALDH1A1 (0.62) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL11292187 | 0.83 | KCNH2 (0.61) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL19621588 | 0.82 | IDO1 (0.61) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11441117 | 0.82 | IDO1 (0.61) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL16594362 | 0.82 | TSHR (0.56) | MAPTLMNASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |