Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12689662 | 1.00 | KMT2A (0.65) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL17549715 | 0.91 | KMT2A (0.61) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL17464405 | 0.91 | KMT2A (0.76) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL71111 | 0.91 | KMT2A (0.78) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL16492078 | 0.91 | KMT2A (0.78) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL11568438 | 0.91 | KMT2A (0.78) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL24784012 | 0.90 | KMT2A (0.53) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL13514851 | 0.88 | KMT2A (0.61) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL12927404 | 0.87 | KMT2A (0.74) | KMT2AMEN1ALDH1A1TSHRHIF1A | |
| SCHEMBL14616787 | 0.87 | KMT2A (0.74) | KMT2AMEN1ALDH1A1TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145545-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-06-19 | — | — | US | disclosed |
| WO-2008073534-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |
| US-7271283-B2 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1512704-A1 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | MACF1, WASF2, THEM6 | KMT2A 2677/4885MEN1 1688/4885ALDH1A1 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.