SCHEMBL4758796

SCHEMBL4758796

C=CC(=O)OC(CSc1nc2ccccc2s1)CSc1nc2ccccc2s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HPGD P15428 3/20 0.55
APEX1 P27695 2/20 0.54
POLB P06746 2/20 0.54
RECQL P46063 1/20 0.54
MAPT P10636 3/20 0.52
MAPK1 P28482 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CYP1A2 P05177 3/20 0.50
CYP2D6 P10635 3/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C19 P33261 2/20 0.50
HIF1A Q16665 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX5 P09917 4/20 0.48
ALPL P05186 1/20 0.47
ALPG P10696 1/20 0.47
GCGR P47871 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25123491 0.89 ALDH1A1 (0.50) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL4756672 0.79 ALDH1A1 (0.59) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL3259609 0.79 ALDH1A1 (0.53) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL9175427 0.77 SMN1; SMN2 (0.56) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL28489985 0.77 POLB (0.51) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL10402125 0.77 APEX1 (0.64) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL9811100 0.76 POLB (0.54) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL25123486 0.75 ALDH1A1 (0.54) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL9175312 0.75 ALDH1A1 (0.54) ALDH1A1HPGDAPEX1POLBRECQL
SCHEMBL9811018 0.75 ALDH1A1 (0.55) ALDH1A1HPGDAPEX1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US claimed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US disclosed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US disclosed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP disclosed
US-20080145545-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM CITIBANK, N.A., AS COLLATERAL AGENT 2008-06-19 US disclosed
WO-2008073534-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 ALDH1A1 1014/4885HPGD 1794/4885APEX1 2754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.