Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 15/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759150 | 1.00 | AVPR1A (0.46) | AVPR1AOXTRHRH3AVPR2 | |
| SCHEMBL4759117 | 0.82 | HSD11B1 (0.61) | AVPR1AHRH3 | |
| SCHEMBL4759115 | 0.82 | HSD11B1 (0.61) | AVPR1AHRH3 | |
| SCHEMBL3682438 | 0.80 | AVPR1A (0.48) | AVPR1AOXTRHRH3AVPR2 | |
| SCHEMBL349521 | 0.76 | HSD11B1 (0.67) | AVPR1AOXTR | |
| SCHEMBL18701840 | 0.74 | AVPR1A (0.58) | AVPR1AOXTRHRH3AVPR2 | |
| SCHEMBL3232343 | 0.74 | AVPR1A (0.57) | AVPR1AHRH3AVPR2 | |
| SCHEMBL3231283 | 0.74 | AVPR1A (0.54) | AVPR1AOXTRHRH3AVPR2 | |
| SCHEMBL5531225 | 0.73 | AVPR1A (0.53) | AVPR1AOXTRHRH3AVPR2 | |
| SCHEMBL4757502 | 0.73 | HSD11B1 (0.52) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758582-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1758582-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006002349-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-01-05 | — | — | WO | claimed |