SCHEMBL4759293 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GGT1	P19440	1/20	0.43

▸	ECE1	P42892	4/20	0.38

▸	ITGB2	P05107	1/20	0.33

▸	ICAM1	P05362	1/20	0.33

▸	ITGAL	P20701	1/20	0.33

▸	MAOA	P21397	1/20	0.32

▸	MAOB	P27338	1/20	0.32

▸	CPB2	Q96IY4	5/20	0.32

▸	CPB1	P15086	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9905502	0.88	CA12 (0.41)	GGT1ECE1ITGB2ICAM1ITGAL
SCHEMBL20477159	0.88	CA12 (0.41)	GGT1ECE1ITGB2ICAM1ITGAL
SCHEMBL27650325	0.85	GGT1 (0.55)	GGT1ECE1ITGB2ICAM1ITGAL
SCHEMBL27902177	0.85	GGT1 (0.46)	GGT1CPB2CPB1
SCHEMBL27650327	0.85	GGT1 (0.55)	GGT1ECE1ITGB2ICAM1ITGAL
SCHEMBL30885854	0.84	MAOA (0.48)	ECE1MAOAMAOB
SCHEMBL3441239	0.83	ECE1 (0.38)	ECE1ITGB2ICAM1ITGAL
SCHEMBL1221420	0.83	ECE1 (0.38)	ECE1ITGB2ICAM1ITGAL
SCHEMBL10724429	0.82	GGT1 (0.46)	GGT1MAOAMAOBCPB2CPB1
SCHEMBL29670111	0.82	GGT1 (0.40)	GGT1ECE1ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008116053-A2	FAP-ACTIVATED CHEMOTHERAPEUTIC COMPOUNDS, AND METHODS OF USE THEREOF	TRUSTEES OF TUFTS COLLEGE (US)	2008-09-25	—	—	WO	disclosed