SCHEMBL475930

SCHEMBL475930

[CH2]C(=O)O[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.33
EPHX1 P07099 5/20 0.33
TSHR P16473 3/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475989 0.93 EPHX1 (0.36) EPHX1TSHRCES2CES1ALDH1A1
SCHEMBL475935 0.91 EPHX1 (0.39) EPHX1TSHRCES2CES1ALDH1A1
SCHEMBL475991 0.91 EPHX1 (0.39) EPHX1TSHRCES2CES1ALDH1A1
SCHEMBL476141 0.91 EPHX1 (0.39) EPHX1TSHRCES2CES1ALDH1A1
SCHEMBL476032 0.86 TDP1 (0.30)
SCHEMBL476045 0.80 LMNA (0.33) ACHEEPHX1TSHRCES2CES1
SCHEMBL476063 0.80 ALDH1A1 (0.34) ACHEEPHX1TSHRCES2CES1
SCHEMBL475932 0.79 ALDH1A1 (0.44) ACHEEPHX1TSHRCES2CES1
SCHEMBL4641558 0.78 CA12 (0.34) ACHEEPHX1TSHRCES2CES1
SCHEMBL1525545 0.78 TSHR (0.50) ACHEEPHX1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed