Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759314 | 0.79 | CA1 (0.45) | CA1CA2CA9CA12PTGS1 | |
| SCHEMBL8724464 | 0.77 | KCNH2 (0.49) | CA1CA2CA9CA12PTGS1 | |
| SCHEMBL10199428 | 0.76 | GRM4 (0.58) | CHEK1GRM4PDCD1CD274 | |
| SCHEMBL8810650 | 0.76 | CA12 (0.37) | CA1CA2CA9CA12 | |
| SCHEMBL16741223 | 0.74 | NOS2 (0.48) | CA1CA2CA9CA12 | |
| SCHEMBL15865503 | 0.74 | NOS3 (0.54) | CHEK1GRM4PDCD1CD274 | |
| SCHEMBL28772935 | 0.74 | CA12 (0.37) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL11606622 | 0.71 | CHEK1 (0.46) | CHEK1GRM4PDCD1CD274PTGS1 | |
| SCHEMBL4073856 | 0.70 | LRRK2 (0.51) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL2896796 | 0.70 | LRRK2 (0.51) | CA1CA2CA9CA12PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |