Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415348 | 0.86 | PTGS2 (0.45) | KCNH2PTGS2PTGS1CA1CA2 | |
| SCHEMBL29800787 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1FEN1ALDH1A1HTT | |
| SCHEMBL26964164 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1FEN1ALDH1A1HTT | |
| SCHEMBL5700114 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1ALDH1A1HTTHSD17B10 | |
| SCHEMBL30553482 | 0.78 | L3MBTL1 (0.43) | KCNH2CA1CA2CA9CA12 | |
| SCHEMBL4759306 | 0.77 | CA1 (0.42) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL30355861 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4574863 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL8697134 | 0.74 | CA1 (0.42) | KCNH2PTGS2PTGS1CA1CA2 | |
| SCHEMBL4759314 | 0.73 | CA1 (0.45) | PTGS2PTGS1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209980-B | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PF MEDICAMENT | 2015-06-03 | — | — | CN | claimed |
| CN-103209980-A | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PF MEDICAMENT | 2013-07-17 | — | — | CN | claimed |
| CN-103209980-B | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PF MEDICAMENT | 2015-06-03 | — | — | CN | disclosed |
| CN-103209980-A | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PF MEDICAMENT | 2013-07-17 | — | — | CN | disclosed |
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| US-4936903-A | HERBICIDES; PLANT GROWTH REGULATORS; RICE CROPS | CIBA-GEIGY CORP. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4875923-A | HERBICIDE | CIBA-GEIGY CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |