Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.58 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 7/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803754 | 0.98 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Bromide SCHEMBL1667281 | 0.96 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL30033466 | 0.95 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5023742 | 0.94 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Bromide SCHEMBL30032600 | 0.91 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL475906 | 0.89 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| SCHEMBL1200572 | 0.87 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| SCHEMBL28417958 | 0.86 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Bromide SCHEMBL30033465 | 0.85 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2GAATSHRALDH1A1 | |
| Iodide SCHEMBL29129904 | 0.85 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2GAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877477-B2 | Temperature-responsive polymer particles in protein separation applications | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL ORGANISATION (AU) | 2014-11-04 | — | — | US | claimed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| EP-1694787-A1 | INK JET INK COMPOSITION | EASTMAN KODAK COMPANY (US) | 2006-08-30 | — | — | EP | claimed |
| EP-1245588-B1 | Composite colorant particles | EASTMAN KODAK CO (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005121262-A1 | AN AQUEOUS INKJET INK COMPOSITION | EASTMAN KODAK COMPANY (US) | 2005-12-22 | — | — | WO | claimed |
| US-20050272831-A1 | Aqueous inkjet ink compositon | EASTMAN KODAK COMPANY | 2005-12-08 | — | — | US | claimed |
| WO-2005066290-A1 | INK JET INK COMPOSITION | EASTMAN KODAK COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| US-20050134665-A1 | Ink jet ink composition | EASTMAN KODAK COMPANY | 2005-06-23 | — | — | US | claimed |
| EP-1201720-B1 | Printing fluid additives promoting overcoat adhesion | HEWLETT PACKARD CO (US) | 2004-09-15 | — | — | EP | claimed |
| US-6610412-B2 | Clear protective thermal transfer overcoating and acrylic polymer compatibilizer; computer prints | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2003-08-26 | — | — | US | claimed |
| US-20030119973-A1 | Printing fluid additives promoting overcoat adhesion | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2003-06-26 | — | — | US | claimed |
| EP-1245589-A1 | Process for making composite colorant particles | EASTMAN KODAK COMPANY (US) | 2002-10-02 | — | — | EP | claimed |
| US-6417249-B1 | INK JET PRINTING INK FOR COLOR VEHICLES, CORE/SHELL BINDERS, SMUDGE PROOF | HEWLETT-PACKARD COMPANY | 2002-07-09 | — | — | US | claimed |
| EP-1201720-A1 | Printing fluid additives promoting overcoat adhesion | Hewlett-Packard Company (US) | 2002-05-02 | — | — | EP | claimed |
| US-6248805-B1 | THERMAL INK JET PRNTING | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | claimed |
| US-6057384-A | VEHICLE AND COLORANT ASSOCIATED WITH A PRIMER CORE/SHELL POLYMER; DURABLR SMEAR-FAST FILM | HEWLETT-PACKARD COMPANY (US) | 2000-05-02 | — | — | US | claimed |
| US-5990202-A | DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY | HEWLETT-PACKARD COMPANY (US) | 1999-11-23 | — | — | US | claimed |
| US-12570860-B2 | Two-component treatment agent, treatment method for making metal surface antibacterial and antibacterial treatment agent | TOKYO OHKA KOGYO CO., LTD. (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-0627324-A1 | Ink jet recording medium | MITSUBISHI PAPER MILLS, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5075197-A | Water based polymer dispersion | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570860-B2 | Two-component treatment agent, treatment method for making metal surface antibacterial and antibacterial treatment agent | SARS1, ACE2, EIF2AK2 | ZDHHC20 1582/4885ZDHHC2 1068/4885GAA 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.