Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229584 | 0.88 | TSHR (0.56) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL575202 | 0.81 | TSHR (0.58) | TSHRPPARDTP53TDP1 | |
| SCHEMBL1563927 | 0.78 | TSHR (0.52) | TSHRPPARDTP53TDP1 | |
| SCHEMBL9770097 | 0.75 | TSHR (0.56) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL1296882 | 0.74 | TSHR (0.61) | TSHRPPARDTP53TDP1 | |
| SCHEMBL29739400 | 0.74 | TSHR (0.48) | TSHRPPARDTP53TDP1 | |
| SCHEMBL26483 | 0.74 | TSHR (1.00) | TSHRPPARDTP53TDP1 | |
| SCHEMBL5961215 | 0.74 | TSHR (1.00) | TSHRPPARDTP53TDP1 | |
| SCHEMBL4758287 | 0.73 | TSHR (0.75) | TSHRPPARDTP53TDP1 | |
| SCHEMBL29723046 | 0.72 | TSHR (0.65) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435841-B2 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20070123492-A1 | Analogs of lysophosphatidic acid and methods of making and using thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-05-31 | — | — | US | disclosed |
| EP-1615937-A2 | ANALOGS OF LYSOPHOSPHATIDIC ACID AND METHODS OF MAKING AND USING THEREOF | University of Utah Research Foundation (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2005086961-A2 | IMPROVED PREPARATION OF HALOHYDROCCARBYL PHOSPHONIC ACID DIESTRES | RHODIA INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA OPERATIONS (FR) | 2005-09-15 | — | — | US | disclosed |
| WO-2004092188-A2 | ANALOGS OF LYSOPHOSPHATIDIC ACID AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | HDHD5, PHYKPL, HPD | TSHR 2066/4885PPARD 274/4885TP53 3640/4885 |
| US-20070123492-A1 | Analogs of lysophosphatidic acid and methods of making and using thereof | LPAR4, LPAR2, LPAR5 | TSHR 2595/4885PPARD 895/4885TP53 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.