Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760263 | 0.83 | HTT (0.50) | KMT2ALMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL3077002 | 0.81 | KMT2A (0.49) | KMT2ALMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL14341235 | 0.73 | EPHX2 (0.56) | KMT2ALMNAALDH1A1EPHX2HTT | |
| SCHEMBL5746460 | 0.72 | ALDH1A1 (0.74) | KMT2ALMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3064580 | 0.72 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL3069824 | 0.71 | MAOB (0.49) | KMT2ALMNAALDH1A1EPHX2HTT | |
| SCHEMBL3054305 | 0.71 | KMT2A (0.49) | KMT2ALMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL3054162 | 0.71 | ALDH1A1 (0.57) | KMT2ALMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL3063917 | 0.70 | HTT (0.57) | KMT2ALMNAALDH1A1EPHX2HTT | |
| SCHEMBL810613 | 0.69 | FAAH (0.46) | KMT2ALMNAALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |