Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680725 | 0.90 | ALDH1A1 (0.71) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL742923 | 0.88 | GPBAR1 (0.65) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL4760150 | 0.86 | CYP3A4 (0.55) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL7196373 | 0.82 | CYP3A4 (0.77) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL7199293 | 0.82 | CYP3A4 (0.77) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL7880195 | 0.82 | GPBAR1 (0.57) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL13932424 | 0.82 | CYP8B1 (0.71) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL13932422 | 0.82 | CYP8B1 (0.68) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL10522671 | 0.81 | GPBAR1 (0.63) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 | |
| SCHEMBL2553341 | 0.81 | GPBAR1 (0.83) | CYP3A4MEN1KMT2ASLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173765-B2 | Polymers, uses and methods of manufacture thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2012-05-08 | — | — | US | disclosed |
| US-20090082542-A1 | NOVEL POLYMERS, USES AND METHODS OF MANUFACTURE THEREOF | UNIVERSITE DE MONTREAL (CA) | 2009-03-26 | — | — | US | disclosed |