Sugi Predict

Sugi Predict / Compounds / Bicarbonate

Bicarbonate

Bicarbonate

SCHEMBL4760182

O=C(O)O.O=C(O)O.O=C([O-])[O-].[Cs+].[Cs+]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.56
▸ CA2 P00918 1/20 0.56
▸ CA9 Q16790 1/20 0.56
▸ CA4 P22748 5/20 0.42
▸ FAHD1 Q6P587 1/20 0.42
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ LDHA P00338 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ FFAR3 O14843 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ FYN P06241 1/20 0.33
▸ OR51E2 Q9H255 1/20 0.31
▸ CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL6168589 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL6241837 0.95 CA4 (0.50) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL8805172 0.95 CA1 (0.50) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL2560104 0.95 CA4 (0.50) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL8776836 0.94 — —
Bicarbonate SCHEMBL10697570 0.89 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL4958654 0.89 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL10821897 0.89 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL2127368 0.89 — —
Bicarbonate SCHEMBL10891679 0.89 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024262012-A1 KIT FOR CARBON DIOXIDE GAS PACK 株式会社アンプリー 2024-12-26 — — WO disclosed
US-11229583-B2 Multilayer nanofiber sheet and adhesion method for same KAO CORPORATION (JP) 2022-01-25 — — US disclosed
EP-1979309-A2 PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN Boehringer Ingelheim International GmbH (DE) 2008-10-15 — — EP disclosed
WO-2007084882-A2 PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-07-26 — — WO disclosed
US-20070173517-A1 Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides WIRTH THOMAS 2007-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173517-A1 Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides ICAM1, CD14, VCAM1 CA1 2571/4885CA2 2683/4885CA9 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.