Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HPGDS | O60760 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750357 | 1.00 | DGAT1 (0.62) | DGAT1CA2CA1NPSR1NPC1 | |
| SCHEMBL9462009 | 0.90 | SLC1A2 (0.66) | DGAT1CA2CA1NPSR1MMP2 | |
| SCHEMBL1168553 | 0.90 | SLC1A2 (0.66) | DGAT1CA2CA1NPSR1MMP2 | |
| SCHEMBL1168551 | 0.90 | SLC1A2 (0.66) | DGAT1CA2CA1NPSR1MMP2 | |
| SCHEMBL1912260 | 0.89 | CA2 (0.62) | DGAT1CA2CA1NPSR1NPC1 | |
| SCHEMBL10286666 | 0.87 | SLC1A2 (0.59) | DGAT1CA2CA1NPSR1NPC1 | |
| SCHEMBL14195921 | 0.86 | NPC1 (0.55) | DGAT1NPSR1NPC1RAB9AHPGDS | |
| SCHEMBL404406 | 0.86 | NPC1 (0.55) | DGAT1NPSR1NPC1RAB9AHPGDS | |
| SCHEMBL7285729 | 0.84 | HPGDS (0.53) | DGAT1CA2CA1NPSR1NPC1 | |
| SCHEMBL4682406 | 0.83 | CA2 (0.65) | CA2CA1NPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986996-A2 | A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | Abiogen Pharma S.p.A. (IT) | 2008-11-05 | — | — | EP | claimed |
| WO-2007088571-A2 | A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | ABIOGEN PHARMA S.P.A. (IT) | 2007-08-09 | — | — | WO | claimed |