SCHEMBL28752184

SCHEMBL28752184

COC(=O)c1ccc(CCBr)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TSHR P16473 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
XDH P47989 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDK1 Q15118 2/20 0.43
PDK2 Q15119 2/20 0.43
PDK3 Q15120 2/20 0.43
PDK4 Q16654 2/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
NPC1 O15118 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL480297 0.87 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL14037636 0.86 PPARG (0.52) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL18703594 0.86 NPC1 (0.56) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL27313872 0.85 CA12 (0.50) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL27312730 0.84 CA12 (0.40) CA12CA1CA2CA9CA14
SCHEMBL15778501 0.83 ALDH1A1 (0.53) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL15661159 0.83 MAPT (0.53) ALDH1A1MAPTSMN1; SMN2TSHRCA12
Hydrochloric Acid SCHEMBL3649467 0.83 ALDH1A1 (0.47) ALDH1A1MAPTSMN1; SMN2TSHRCA12
SCHEMBL28761815 0.83 MAPT (0.48) ALDH1A1MAPTSMN1; SMN2CA12CA1
SCHEMBL4760486 0.83 KDM4E (0.50) ALDH1A1MAPTSMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1606553-A Oxytocin agonistenoxytocin agonisten FERRING BV (NL) 2005-04-13 CN disclosed