Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452803 | 0.82 | SCN9A (0.48) | SLC22A12MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL18240869 | 0.79 | MEN1 (0.46) | SLC22A12MEN1KMT2AALDH1A1KAT6A | |
| SCHEMBL197671 | 0.74 | HSD11B1 (0.56) | ALDH1A1CYP3A4CYP2D6ALOX15MAPK1 | |
| SCHEMBL8022901 | 0.72 | HSD11B1 (0.54) | ALDH1A1CYP3A4CYP2D6ALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL29010139 | 0.72 | HSD11B1 (0.54) | ALDH1A1CYP3A4CYP2D6ALOX15MAPK1 | |
| SCHEMBL17698979 | 0.71 | SLC22A12 (0.60) | SLC22A12MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL7368671 | 0.70 | MEN1 (0.41) | SLC22A12MEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL20345310 | 0.70 | MEN1 (0.56) | SLC22A12MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL4029025 | 0.69 | SLC22A12 (0.58) | SLC22A12MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL1767681 | 0.69 | SLC22A12 (0.58) | SLC22A12MEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919869-A1 | NOVEL INDOLE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026097-A1 | NOVEL INDOLE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2007-03-08 | — | — | WO | disclosed |