Toluene

Toluene

SCHEMBL4761069

Cc1ccccc1.O=S(=O)(O)NCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
TSHR P16473 2/20 0.50
ALOX12 P18054 2/20 0.50
ACHE P22303 1/20 0.50
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 2/20 0.40
GAA P10253 2/20 0.40
CES2 O00748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL6535761 0.98 LMNA (0.48) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL2490584 0.85 TSHR (0.61) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL30489134 0.85 TSHR (0.61) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL28102361 0.85 TSHR (0.61) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL4909843 0.84 LMNA (0.52) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL10798623 0.84 TSHR (0.52) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL1148280 0.83 LMNA (0.58) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL248686 0.83 LMNA (0.65) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL11123126 0.83 LMNA (0.65) LMNATSHRALOX12ACHECA12
Toluene SCHEMBL761209 0.82 LMNA (0.50) LMNATSHRALOX12ACHECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100577786-C Stable nonaqueous bleaching detergent composition dispersion JOHNSON DIVERSEY INC 2010-01-06 CN claimed
WO-2006026048-A2 BLEACHING WITH IMPROVED WHITENING THE CLOROX COMPANY (US) 2006-03-09 WO claimed
EP-0431002-B1 A DISINFECTING OR BLEACHING TISSUE PAL INT LTD (GB) 1994-03-02 EP claimed
CN-100577786-C Stable nonaqueous bleaching detergent composition dispersion JOHNSON DIVERSEY INC 2010-01-06 CN disclosed
US-20080263778-A1 Stable Nonaqueous Bleaching Detergent Composition Dispersion DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) 2008-10-30 US disclosed
CN-1977037-A Stable non-aqueous bleaching detergent composition dispersions JOHNSON DIVERSEY INC (US) 2007-06-06 CN disclosed
EP-1778827-A1 STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION JohnsonDiversey, Inc., Renee J. Rymarz (US) 2007-05-02 EP disclosed
WO-2006026048-A2 BLEACHING WITH IMPROVED WHITENING THE CLOROX COMPANY (US) 2006-03-09 WO disclosed
WO-2006014223-A1 STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION JOHNSONDIVERSEY, INC. (US) 2006-02-09 WO disclosed
EP-1614741-A1 Stable nonaqueous bleaching detergent composition dispersion JohnsonDiversey, Inc. (US) 2006-01-11 EP disclosed
US-5972866-A HYPOCHLORITE BLEACH USED TO REDUCE STAINING ON THE SURFACE, AN ALKALINITY SOURCE TO PROVIDE A PH OF FROM ABOUT 10 TO 14, A THICKENING AGENT TO PROMOTE ADHESION OF THE COMPOSITION TO THE SURFACE UPON APPLICATION, AND A BALANCE OF WATER. ECOLAB, INC. (US) 1999-10-26 US disclosed
US-5185096-A Containing water soluble alkali metal iodate stabilizer COLGATE-PALMOLIVE CO. (US) 1993-02-09 US disclosed
EP-0517312-A1 Linear viscoelastic aqueous liquid automatic dishwasher detergent composition Colgate-Palmolive Company (US) 1992-12-09 EP disclosed
US-5164106-A Nonaqueous liquid automatic dishwasher detergent composition containing a dual bleach system COLGATE-PALMOLIVE COMPANY (US) 1992-11-17 US disclosed
US-5108641-A Hypochlorite ion source bromide ion source; improved cleaning, storage stability COLGATE-PALMOLIVE CO. (US) 1992-04-28 US disclosed
US-5076952-A Aqueous liquid automatic dishwasher detergent composition containing a dual bleach system AHMED FAHM U (US) 1991-12-31 US disclosed
EP-0423014-A2 Nonaqueous liquid automatic dishwasher detergent composition containing a dual bleach system Colgate-Palmolive Company (US) 1991-04-17 EP disclosed
EP-0395186-A2 Automatic dishwasher detergent composition containing dual bleach system Colgate-Palmolive Company (US) 1990-10-31 EP disclosed
EP-0053387-A1 Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1982-06-09 EP disclosed
US-4211762-A Specific binding assay techniques HUGGINS KEITH G 1980-07-08 US disclosed