Toluene

Toluene

SCHEMBL761209

Cc1ccccc1.NNS(=O)(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
TSHR P16473 2/20 0.50
ALOX12 P18054 2/20 0.50
ACHE P22303 1/20 0.50
ALDH1A1 P00352 4/20 0.42
CYP3A4 P08684 3/20 0.42
MAPT P10636 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 2/20 0.42
GFER P55789 2/20 0.42
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9416863 1.00 LMNA (0.50) LMNATSHRALOX12ACHEALDH1A1
P-Xylene SCHEMBL9416770 0.88 ALDH1A1 (0.48) LMNAACHEALDH1A1MAPTCA1
Toluene SCHEMBL2490584 0.85 TSHR (0.61) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL30489134 0.85 TSHR (0.61) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL28102361 0.85 TSHR (0.61) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL10798623 0.84 TSHR (0.52) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL821885 0.83 TSHR (0.58) LMNATSHRALOX12ACHECA1
Toluene SCHEMBL11123126 0.83 LMNA (0.65) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL248686 0.83 LMNA (0.65) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL4761069 0.82 LMNA (0.50) LMNATSHRALOX12ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4320258-B2 2009-08-26 JP claimed
EP-1580221-B1 Process for the preparation of solid blowing agent compositions LANXESS DEUTSCHLAND GMBH (DE) 2008-10-01 EP claimed
EP-1444306-B1 CURABLE BONDED ASSEMBLIES CAPABLE OF BEING DISSOCIATED DEGUSSA (DE) 2007-04-04 EP claimed
EP-1580220-A1 Solid blowing agent compositions and process for their preparation Lanxess Deutschland GmbH (DE) 2005-09-28 EP claimed
EP-1580221-A1 Solid blowing agent compositions and process for their preparation Lanxess Deutschland GmbH (DE) 2005-09-28 EP claimed
JP-2005525433-A 2005-08-25 JP claimed
EP-1444306-A1 CURABLE BONDED ASSEMBLIES CAPABLE OF BEING DISSOCIATED Degussa AG (DE) 2004-08-11 EP claimed
US-6716778-B1 Seam joining a waterproof laminate with textile layer made of multi-component yarns HOTTNER MARTIN (DE) 2004-04-06 US claimed
EP-0942826-B1 WATERPROOF, BREATHABLE LAMINATE GORE W L & ASS GMBH (DE) 2003-09-17 EP claimed
WO-2003042315-A1 CURABLE BONDED ASSEMBLIES CAPABLE OF BEING DISSOCIATED DEGUSSA AG (DE) 2003-05-22 WO claimed
JP-2002513345-A 2002-05-08 JP claimed
EP-0942826-A1 WATERPROOF, BREATHABLE LAMINATE W.L. GORE & ASSOCIATES GmbH (DE) 1999-09-22 EP claimed
WO-1999016616-A1 WATERPROOF, BREATHABLE LAMINATE W.L. GORE & ASSOCIATES GMBH (DE) 1999-04-08 WO claimed
WO-1999016620-A1 SEAM JOINING A WATERPROOF LAMINATE WITH TEXTILE LAYER MADE OF MULTI-COMPONENT YARNS W. L. GORE & ASSOCIATES, INC. (US) 1999-04-08 WO claimed
WO-1999016943-A1 BI-COMPONENT TEXTILE WITH PROPELLANT W.L. GORE & ASSOCIATES GMBH (DE) 1999-04-08 WO claimed
EP-0906824-A1 Laminate with textile layer made of bicomponent yarn W.L. GORE & ASSOCIATES GmbH (DE) 1999-04-07 EP claimed
EP-0906972-A1 Bi-component textile with propellant W.L. GORE & ASSOCIATES GmbH (DE) 1999-04-07 EP claimed
CN-116102896-A Regenerated artificial board and preparation method thereof 中科广化(重庆)新材料研究院有限公司 2023-05-12 CN disclosed
EP-0131472-A2 5-Mercapto-1,2,3-thiadiazoles composition and process for preparing the same UBE INDUSTRIES, LTD. (JP) 1985-01-16 EP disclosed
EP-0040729-A2 Granular powder agglomerates, and process for preparing same BAYER AG (DE) 1981-12-02 EP disclosed