Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599259 | 0.86 | ALDH1A1 (0.36) | CES2CES1ALDH1A1MAPTTSHR | |
| SCHEMBL2184635 | 0.84 | ELANE (0.41) | CES2CES1ALDH1A1MAPTTSHR | |
| SCHEMBL4189737 | 0.83 | ALDH1A1 (0.34) | CES2CES1ALDH1A1MAPTTSHR | |
| SCHEMBL4189734 | 0.83 | ALDH1A1 (0.34) | CES2CES1ALDH1A1MAPTTSHR | |
| SCHEMBL8795081 | 0.83 | ELANE (0.41) | ALDH1A1TSHRHSD17B10TDP1ELANE | |
| SCHEMBL476116 | 0.83 | TDP1 (0.34) | CES2CES1ALDH1A1MAPTTSHR | |
| SCHEMBL2189980 | 0.82 | THRB (0.38) | ALDH1A1MAPTTSHRHSD17B10TDP1 | |
| SCHEMBL5974325 | 0.81 | HCAR2 (0.37) | ALDH1A1MAPTTSHRHSD17B10TDP1 | |
| SCHEMBL5973451 | 0.81 | HCAR2 (0.37) | ALDH1A1MAPTTSHRHSD17B10TDP1 | |
| SCHEMBL6072557 | 0.81 | ABL1 (0.35) | MAPTTSHRKCNN4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010318-A1 | PROCESSES FOR THE PREPARATION OF ROXADUSTAT AND INTERMEDIATES THEREOF | Teva Pharmaceuticals International GmbH (CH) | 2022-06-15 | — | — | EP | claimed |
| WO-2021026307-A1 | PROCESSES FOR THE PREPARATION OF ROXADUSTAT AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2021-02-11 | — | — | WO | claimed |
| CN-110382634-B | Composition comprising a metal oxide and a metal oxide | 佐敦有限公司 | 2022-01-11 | — | — | CN | disclosed |
| WO-2018158436-A1 | COMPOSITION | JOTUN A/S (NO) | 2018-09-07 | — | — | WO | disclosed |
| EP-2912120-B1 | ANTIFOULING COATING COMPOSITION | JOTUN AS (NO) | 2017-12-20 | — | — | EP | disclosed |
| EP-2935288-B1 | SILYL ESTER COPOLYMER | JOTUN AS (NO) | 2016-10-19 | — | — | EP | disclosed |
| EP-2725073-B1 | Antifouling coating composition | JOTUN AS (NO) | 2016-08-03 | — | — | EP | disclosed |
| EP-2912120-A1 | ANTIFOULING COATING COMPOSITION | Jotun A/S (NO) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014064048-A1 | ANTIFOULING COATING COMPOSITION | JOTUN A/S (NO) | 2014-05-01 | — | — | WO | disclosed |
| WO-2014064049-A1 | ANTIFOULING COATING COMPOSITION | JOTUN A/S (NO) | 2014-05-01 | — | — | WO | disclosed |
| EP-2725073-A1 | Antifouling coating composition | Jotun A/S (NO) | 2014-04-30 | — | — | EP | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| WO-2009149919-A1 | BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER | JOTUN A/S (NO) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009007276-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2009-01-15 | — | — | WO | disclosed |
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| CN-100374296-C | Lithographic process involving on press development | FUJI PHOTO FILM CO LTD (JP) | 2008-03-12 | — | — | CN | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
| CN-1575975-A | Lithographic process involving on press development | FUJI PHOTO FILM CO LTD (JP) | 2005-02-09 | — | — | CN | disclosed |
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |